Seachem Prime™ is the complete and concentrated conditioner for both fresh and salt water. Prime™ removes chlorine, chloramine and ammonia. Prime™ converts ammonia into a safe, non-toxic form that is readily removed by the tank’s biofilter. Prime™ may be used during tank cycling to alleviate ammonia/nitrite toxicity. Prime™ detoxifies nitrite and nitrate, allowing the biofilter to more efficiently remove them. Prime™ also promotes the production and regeneration of the natural slime coat. Prime™ is non-acidic and will not impact pH. Prime™ will not overactivate skimmers. Use at start-up and whenever adding or replacing water. A 250 mL bottle treats over 2,500 gallons, much more than competing products. Marine and freshwater.